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Association between multi-pollutant mixtures pollution and daily cardiovascular mortality: An exploration of exposure-response relationship
Tong, Yuanren1,2; Luo, Kai3,4; Li, Runkui5,6; Pei, Lu3,4; Li, Ang3,4; Yang, Mingan7; Xu, Qun3,4
2018-08-01
Source PublicationATMOSPHERIC ENVIRONMENT
ISSN1352-2310
Volume186Pages:136-143
Corresponding AuthorXu, Qun(xuqun@ibms.cams.cn)
AbstractEvidence of combined mortality effects of multi-pollutant on cardiovascular diseases (CVD) and the corresponding exposure-response (ER) relationship is limited. In this paper, we examined the association between four ambient air pollutants (i.e., fine particulate matter, PM2.5, particulate matter, PM10, nitrogen dioxide, NO2, and sulfur dioxide, SO2.) and CVD mortality and the corresponding ER relationship after incorporating the potential interaction among the multiple pollutants. Bayesian kernel machine regression (BKMR) was used to evaluate the ER relationship and to explore the interactions between pollutants. The results showed that PMio and SO2 were dominant pollutants from 0 to 2 days, while PM2.5 and NO2 had strong effect on CVD mortality from 3 to 4 days. Generally, PM2.5 and NO2 had the similar ER relationship across different moving average concerning the CVD mortality. For the interaction among the multiple pollutants, we found that there is no interaction between partide pollutants (i.e. PM2.5 and PM10) and gaseous pollutants (i.e.NO2 and SO2). On the contrary, there might be an interaction between PM2.5 and PM10 though this interaction was detected by visually comparing the slopes of ER curves of a given particle pollutant at different levels of the other particle pollutant. But there is a lack of statistical significance test for this interaction. This study suggests that different ambient air pollutants might have the dominant effect on CVD deaths during different moving average, though there might not be statistical significant interactions among the ambient air pollutants in present study.
KeywordAir pollution Bayesian kernel machine regression Exposure-relationship Cardiovascular mortality
DOI10.1016/j.atmosenv.2018.05.034
WOS KeywordAMBIENT AIR-POLLUTION ; TIME-SERIES ; PARTICULATE MATTER ; HUMAN HEALTH ; DISEASE ; CHINA ; FINE ; REGRESSION ; IMPACT ; CITY
Indexed BySCI
Language英语
Funding ProjectGong-Yi Program of the Chinese Ministry of Environmental Protection[200909016] ; China Medical Board[15-230] ; Chinese Academy of Medical Science Innovation Fund for Medical Sciences[2017-I2M-1-009]
Funding OrganizationGong-Yi Program of the Chinese Ministry of Environmental Protection ; China Medical Board ; Chinese Academy of Medical Science Innovation Fund for Medical Sciences
WOS Research AreaEnvironmental Sciences & Ecology ; Meteorology & Atmospheric Sciences
WOS SubjectEnvironmental Sciences ; Meteorology & Atmospheric Sciences
WOS IDWOS:000436202500012
PublisherPERGAMON-ELSEVIER SCIENCE LTD
Citation statistics
Document Type期刊论文
Identifierhttp://ir.igsnrr.ac.cn/handle/311030/54668
Collection中国科学院地理科学与资源研究所
Corresponding AuthorXu, Qun
Affiliation1.Chinese Acad Med Sci, Beijing 100005, Peoples R China
2.Peking Union Med Coll, Beijing 100005, Peoples R China
3.Chinese Acad Med Sci, Peking Union Med Coll, Sch Basic Med, Inst Basic Med Sci,Dept Epidemiol & Biostat, Beijing 100005, Peoples R China
4.Chinese Acad Med Sci, Peking Union Med Coll, Ctr Environm & Hlth Sci, Beijing 100005, Peoples R China
5.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China
6.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, Beijing 100101, Peoples R China
7.San Diego State Univ, Grad Sch Publ Hlth, Div Biostat & Epidemiol, San Diego, CA 92182 USA
Recommended Citation
GB/T 7714
Tong, Yuanren,Luo, Kai,Li, Runkui,et al. Association between multi-pollutant mixtures pollution and daily cardiovascular mortality: An exploration of exposure-response relationship[J]. ATMOSPHERIC ENVIRONMENT,2018,186:136-143.
APA Tong, Yuanren.,Luo, Kai.,Li, Runkui.,Pei, Lu.,Li, Ang.,...&Xu, Qun.(2018).Association between multi-pollutant mixtures pollution and daily cardiovascular mortality: An exploration of exposure-response relationship.ATMOSPHERIC ENVIRONMENT,186,136-143.
MLA Tong, Yuanren,et al."Association between multi-pollutant mixtures pollution and daily cardiovascular mortality: An exploration of exposure-response relationship".ATMOSPHERIC ENVIRONMENT 186(2018):136-143.
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