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Ecological analysis of Kashin-Beck osteoarthropathy risk factors in Tibet's Qamdo City, China
Zha, Xinjie1,2; Gao, Xing1
2019-02-21
Source PublicationSCIENTIFIC REPORTS
ISSN2045-2322
Volume9Pages:8
Corresponding AuthorGao, Xing(gxing@igsnrr.ac.cn)
AbstractWe studied Tibet's Qamdo City, which currently hosts the most serious prevalence of Kashin-Beck osteoarthropathy (KB) in China. This study utilizes the geographical detector (GeoDetector) algorithm to measure the individual and interactive influences of risk factors on KB and to quantify the highest potential risk subzones of each principal factor. With a comprehensive consideration of 13 possible related factors, namely, the tectonic division, stratum, moisture index, gross domestic product, mean annual precipitation, soil type, groundwater type, elevation, mean annual temperature, vegetation type, geomorphic type, slope degree and slope aspect, our results indicate that the main exposure factors for KB in Qamdo City are geological factors (tectonic division and stratum), wetting factors (moisture index and mean annual precipitation), and an economic factor (gross domestic product). In contrast, other factors have little effect on the prevalence of KB in Qamdo City. All 13 factors either nonlinearly or bivariately enhance each other, and the interactions between these factors can increase the prevalence of KB. Consequently, it can be inferred that KB in Qamdo City is caused primarily by a set of multiple and interrelated disease risk factors.
DOI10.1038/s41598-019-39792-0
WOS KeywordFUNGAL CONTAMINATION ; DRINKING-WATER ; DISEASE ; SELENIUM ; HEALTH ; IODINE ; SOIL ; DEFICIENCY ; DEFECTS ; FINLAND
Indexed BySCI
Language英语
Funding ProjectStrategic Priority Research Program of the Chinese Academy of Sciences[XDA19040305] ; Foundation of the State Key Laboratory of Resources and Environmental Information System[O88RAA0BYA] ; Scientific Research Project of Tibet Autonomous Region[XZ201801NA02]
Funding OrganizationStrategic Priority Research Program of the Chinese Academy of Sciences ; Foundation of the State Key Laboratory of Resources and Environmental Information System ; Scientific Research Project of Tibet Autonomous Region
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000459281500040
PublisherNATURE PUBLISHING GROUP
Citation statistics
Document Type期刊论文
Identifierhttp://ir.igsnrr.ac.cn/handle/311030/49474
Collection中国科学院地理科学与资源研究所
Corresponding AuthorGao, Xing
Affiliation1.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Zha, Xinjie,Gao, Xing. Ecological analysis of Kashin-Beck osteoarthropathy risk factors in Tibet's Qamdo City, China[J]. SCIENTIFIC REPORTS,2019,9:8.
APA Zha, Xinjie,&Gao, Xing.(2019).Ecological analysis of Kashin-Beck osteoarthropathy risk factors in Tibet's Qamdo City, China.SCIENTIFIC REPORTS,9,8.
MLA Zha, Xinjie,et al."Ecological analysis of Kashin-Beck osteoarthropathy risk factors in Tibet's Qamdo City, China".SCIENTIFIC REPORTS 9(2019):8.
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