IGSNRR OpenIR
Simultaneous analysis of typical halogenated endocrine disrupting chemicals and metal(loid)s in human hair
Ren, Mengyuan1,2; Jia, Xiaoqian1,2; Shi, Jiazhang3; Yan, Lailai5; Li, Zewu1,2; Lan, Changxin1,2; Chen, Junxi1,2; Li, Nan1,2; Li, Kexin6; Huang, Jing3,4; Wu, Shaowei3,4; Lu, Qun7; Li, Zhiwen1,2; Wang, Bin1,2; Liu, Jianmeng1,2
2020-05-20
Source PublicationSCIENCE OF THE TOTAL ENVIRONMENT
ISSN0048-9697
Volume718Pages:10
Corresponding AuthorLi, Zhiwen(lizw@bjmu.edu.cn) ; Wang, Bin(binwangpku@foxmail.com)
AbstractHair analysis has been an important approach in evaluating population exposure to various environmental fac-tors. To meet the requirements of human environmental epidemiology studies, we aimed to develop an efficient method for simultaneous analysis of various metal(loid)s and some typical environmental halogenated endo-crine disrupting chemicals (hEDCs) (i.e., polychlorinated biphenyls, polybrominated diphenyl ethers, and organ-ochlorine pesticides, as well as some of their hydroxyl substituted metabolites) in a single hair sample. The hair was washed successively with surfactant solutions, methanol solvent, and deionized water to remove impurities attached to the hair surface. Efficiency was comprehensively compared among various washing strategies. The hair sample was further pulverized into line powder with a median diameter (25th-75th percentile) of 8.6 (5.9-13.5) mu m. The hair organic components were extracted by acetonitrile solvent and compared with the microwave-assisted extraction method. The hEDCs in the supernatant acetonitrile phase were quantified by gas chromatography-mass spectrometry, and the metal(loid)s in the precipitate hair were further analyzed by inductively coupled plasma mass spectrometry. Our developed method was further applied to analyze the hair samples of 165 pregnant women. The results showed that particles attached to the surface of the hair could not be washed off completely. However, we proposed a protocol framework to wash hair with relatively high efficience, which includes warm water incubation, and use of surfactant and organic solvent. The recoveries of the concerned hEDCs and metal( loid)s were overall in the range of 80% to 120%. For the women population, the method can efficiently recognize the typical exposure characteristics of the concerned hEDCs and metal(loid)s. Our study significantly ameliorated the deficiencies of the traditional hair washing strategy and developed an efficient method for simultaneous analysis of various metal(loid)s and hEDCs in a single hair sample. This method will provide important support for population complex exposure analysis and facilitate environmental exposome studies. (C) 2020 Elsevier B.V. All rights reserved.
KeywordHair Simultaneous analysis Endocrine disrupting chemicals Metal(loid)s Exposome
DOI10.1016/j.scitotenv.2020.137300
WOS KeywordPOLYCYCLIC AROMATIC-HYDROCARBONS ; NEURAL-TUBE DEFECTS ; RARE-EARTH-ELEMENTS ; POLYBROMINATED DIPHENYL ETHERS ; SOLID-PHASE MICROEXTRACTION ; ASSISTED SOLVENT-EXTRACTION ; MASS-SPECTROMETRY ; MATERNAL HAIR ; E-WASTE ; POLYCHLORINATED-BIPHENYLS
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[41771527] ; National Natural Science Foundation of China[81673177] ; National Natural Science Foundation of China[41830641]
Funding OrganizationNational Natural Science Foundation of China
WOS Research AreaEnvironmental Sciences & Ecology
WOS SubjectEnvironmental Sciences
WOS IDWOS:000526029000127
PublisherELSEVIER
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.igsnrr.ac.cn/handle/311030/133816
Collection中国科学院地理科学与资源研究所
Corresponding AuthorLi, Zhiwen; Wang, Bin
Affiliation1.Peking Univ, Inst Reprod & Child Hlth, Beijing 100191, Peoples R China
2.Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China
3.Peking Univ, Dept Occupat & Environm Hlth Sci, Sch Publ Hlth, Beijing 100191, Peoples R China
4.Peking Univ, Key Lab Mol Cardiovasc Sci, Minist Educ, Beijing, Peoples R China
5.Peking Univ, Sch Publ Hlth, Dept Laboratorial Sci & Technol, Beijing 100191, Peoples R China
6.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China
7.Peking Univ, Peoples Hosp, Reprod Med Ctr, Beijing 100044, Peoples R China
Recommended Citation
GB/T 7714
Ren, Mengyuan,Jia, Xiaoqian,Shi, Jiazhang,et al. Simultaneous analysis of typical halogenated endocrine disrupting chemicals and metal(loid)s in human hair[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2020,718:10.
APA Ren, Mengyuan.,Jia, Xiaoqian.,Shi, Jiazhang.,Yan, Lailai.,Li, Zewu.,...&Liu, Jianmeng.(2020).Simultaneous analysis of typical halogenated endocrine disrupting chemicals and metal(loid)s in human hair.SCIENCE OF THE TOTAL ENVIRONMENT,718,10.
MLA Ren, Mengyuan,et al."Simultaneous analysis of typical halogenated endocrine disrupting chemicals and metal(loid)s in human hair".SCIENCE OF THE TOTAL ENVIRONMENT 718(2020):10.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Ren, Mengyuan]'s Articles
[Jia, Xiaoqian]'s Articles
[Shi, Jiazhang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Ren, Mengyuan]'s Articles
[Jia, Xiaoqian]'s Articles
[Shi, Jiazhang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Ren, Mengyuan]'s Articles
[Jia, Xiaoqian]'s Articles
[Shi, Jiazhang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.